Precursor Lesions for Prostate Cancer
نویسندگان
چکیده
منابع مشابه
Prostate Cancer Precursor Diseases
Prostate cancer remains the most common non-cutaneous malignancy in the Western world and is the second leading cause of cancer death in males, after lung cancer (Nelson et al., 2003; Papatsoris & Anagnostopoulos, 2009). Based on experimental and preclinical findings, novel anti-prostate cancer strategies have been developed (Papatsoris & Papavassiliou, 2001; Papatsoris et al., 2005). However, ...
متن کاملPrecursor lesions for liver cancer in humans.
Our knowledge of the cellular changes that lead to liver cell carcinoma in humans is limited by proper and necessary ethical restriction on clinical research. We know rather more about risk factors, the most important of which is cirrhosis, it seems that both the causative agent and the time of duration of the cirrhotic process are relevent to the magnitude of this risk. According to present kn...
متن کاملPrecursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN
Pancreatic cancer is still a dismal disease. The high mortality rate is mainly caused by the lack of highly sensitive and specific diagnostic tools, and most of the patients are diagnosed in an advanced and incurable stage. Knowledge about precursor lesions for pancreatic cancer has grown significantly over the last decade, and nowadays we know that mainly three lesions (PanIN, and IPMN, MCN) a...
متن کاملMolecular Analysis of Precursor Lesions in Familial Pancreatic Cancer
BACKGROUND With less than a 5% survival rate pancreatic adenocarcinoma (PDAC) is almost uniformly lethal. In order to make a significant impact on survival of patients with this malignancy, it is necessary to diagnose the disease early, when curative surgery is still possible. Detailed knowledge of the natural history of the disease and molecular events leading to its progression is therefore c...
متن کاملHedgehog Signaling Links Chronic Inflammation to Gastric Cancer Precursor Lesions
Since its initial discovery in Drosophila, Hedgehog (HH) signaling has long been associated with foregut development. The mammalian genome expresses 3 HH ligands, with sonic hedgehog (SHH) levels highest in the mucosa of the embryonic foregut. More recently, interest in the pathway has shifted to improving our understanding of its role in gastrointestinal cancers. The use of reporter mice prove...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the Royal Society of Medicine
سال: 1997
ISSN: 0141-0768,1758-1095
DOI: 10.1177/014107689709001003